Efficient 3D pharmacophore alignment as a tool for structure-based modeling and scoring
نویسندگان
چکیده
منابع مشابه
Efficient 3D pharmacophore alignment as a tool for structure-based modeling and scoring
Chemical-feature based pharmacophore models have been established as state-of-the-art technique for bioactivity prediction. While in ligand-based drug design, chemical feature-based pharmacophore creation from a set of bio-active molecules is a frequently chosen approach, structure-based pharmacophores are still lacking the reputation to be an alternative or at least a supplement to docking tec...
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ژورنال
عنوان ژورنال: Chemistry Central Journal
سال: 2008
ISSN: 1752-153X
DOI: 10.1186/1752-153x-2-s1-p49